Rachael McGuinness appeared on Coronation Street in three different roles:
- A Croupier at Monogram casino in February and May 2011
- Lindsey, nemesis of Beth Sutherland, who attended a Weatherfield Comprehensive class of 1991 reunion at Nick's Bistro in June 2016
- Kelly, a guest at a Blackpool B&B, who in January 2019 had been taken in by the deceptive Jude Appleton.
Having trained at both Hull University and Liverpool Institute of Performing Arts, she has also been credited for roles in Wire in the Blood, Emmerdale, Doctors and Being Human, whilst on stage she has appeared in productions including Roberto Zucco, Beautiful Thing, Woyzeck, Pericles, Miss Julie, Macbeth, Snapshots and Triptych.