Karen Asemper appeared on Coronation Street in five roles:
- A receptionist at the Doveridge Hall Hotel in February 2004
- A nurse in August 2008 and January 2009
- Child Welfare Officer Helen Kaye in September 2010
- Social worker Carol in July 2017
- PC Garner between March and April 2020.
She trained at the Northern School of Contemporary Dance, graduating in 1995 with a BpA Degree in Contemporary Dance.
Her other credits include roles in Always and Everyone, Where the Heart Is, Lawless, Doctors, Eleventh Hour, Blue Murder, Hustle, Emmerdale, Wolfblood, Cold Feet, Malpractice and The Crown, along with the films Goal II: Living the Dream and Last Laugh.
On stage, she appeared in productions of Romeo and Juliet, Widening Participation and Dirty Money.