Barlow's Bookies was the central bookmakers of Weatherfield, located at 19 Rosamund Street. The business was originally opened by Peter Barlow in October 2001 although he left the area in November 2003 and the business and upstairs accommodation went into the hands of solicitors. In December 2007, bookmaker Harry Mason and his son Dan bought the premises and opened Harry Mason Turf Accountant, however they were forced to sell up less than a year later in November 2008 after they fell on hard times. Upon receiving a large amount of money left in his former wife Lucy's will, Peter bought the bookies back, although the signage remained unaltered until January 2009.
One of the most memorable storylines involving the bookies occurred in mid-2010 when Lewis Archer conned Peter out of £4,000 by placing false betting slips into the till while Deirdre Barlow wasn't looking. On 4th September 2011, Carla Connor crashed her car into the premises and knocked Stella Price down. After ex-wife Leanne married Nick Tilsley she started working at Nick's Bistro and needed to sell her share of the bookies. Peter wanted to buy her out but didn't have the money and the bookies was losing both money and customers. With Carla - now Peter's new partner - hating them working with each other, she decided to buy Leanne's share behind Peter's back. With Carla not knowing anything about the business she went to her brother Rob Donovan (who was a shareholder in Underworld) and he kitted the bookies out with new computers, televisions and a new coffee machine. He also put up a new sign up as he thought the old one was tacky and run down. In July 2013, Rob placed a £500 accumulator bet which came in and won him £35,190. As Peter was unable to pay up in full, Peter was forced to close the business and agreed to let the premises rent-free to Rob and his stepsister Tracy Barlow as part of their reimbursement, and they opened a cash converters shop in the premises which they named Barlow's Buys.
- Peter Barlow - Owner/Co-owner (2001-2003, 2009-2013)
- Sally Webster - Clerk (2002-2003)
- Tracy Preston - Clerk (2003)
- Lucy Barlow - Temporary Manager (2003)
- Shelley Barlow - Temporary Manager (2003)
- Leanne Battersby - Clerk/Co-owner (2009-2013)
- Blanche Hunt - Temporary Clerk (2009)
- Michelle Connor - Clerk (2009)
- Deirdre Barlow - Clerk (2010)
- John Stape - Clerk (2010-2011)
- Nick Tilsley - Temporary Manager (2010-2011)
- Carla Connor - Co-owner (2013)
- Rob Donovan - Manager (2013)